蔡軍，1975年生，籍貫湖北荊州，中國醫(yī)學(xué)科學(xué)院阜外醫(yī)院主任醫(yī)師，博士生導(dǎo)師。1995年考入同濟(jì)醫(yī)科大學(xué)臨床醫(yī)學(xué)專業(yè)，2000年獲得學(xué)士學(xué)位。2001年在武漢大學(xué)內(nèi)科學(xué)專業(yè)攻讀博士學(xué)位，從事心血管內(nèi)科研究。2007年進(jìn)入哈佛醫(yī)學(xué)院麻省總醫(yī)院進(jìn)行博士后研究工作，主要研究心肌重構(gòu)機制。2009年為副主任醫(yī)師，2012年為主任醫(yī)師。

圍繞高血壓人群防治和發(fā)病機制開展系列創(chuàng)新性研究。以血管發(fā)育、重構(gòu)相關(guān)易感基因為核心，腸道菌群穩(wěn)態(tài)失調(diào)為切入點，通過新一代組學(xué)技術(shù)，揭示高血壓病因，并展開臨床試驗，為高血壓預(yù)防和干預(yù)提供證據(jù)和理論基礎(chǔ)。

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1. Fan L #, Chen J#, Pan L#, Xin X#, Geng B, Yang L, Wang Q, Ma W, Lou Y, Bian J, Cui X, Li J, Wang L, Chen Z, Wang W, Cui C, Li S, Gao Q, Song Q, Deng Y, Fan J, Yu J, Zhang H*, Li Y*, Cai J*, Alterations of gut microbiome, metabolome and lipidome in Takayasu arteritis. Arthritis & Rheumatology. 2022. Accepted (IF=15.483)

2. Chen Z#, Ouyang C#, Zhang H, Gu Y, Deng Y, Du C, Cui C, Li S, Wang W, Kong W, Chen J#, Cai J*, Geng B*. Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy.Autophagy. 2022; 28;1-18.(IF=16.016)

3. Liu X#, Chen Z#, Li S#, Jin L, Cui X, Cui C, Deng Y, Gao Q, Fan L, Niu Y, Wang W, Cui C, Zhong J, Cui Q*, Geng B*, Cai J*.Pre-miRNA Hsa-Let-7a-2: a Novel Intracellular Partner of Angiotensin II Type 2 Receptor Negatively Regulating its Signals.Int J Biol Sci. 2022;18(8):3237-3250. (IF=10.750)

4. Zhang W#*, Zhang S#, Deng Y#, Wu S#, Ren J#, Sun G#, Yang J#, Jiang Y#, Xu X#, Wang TD#, Chen Y#, Li Y, Yao L, Li D, Wang L, Shen X, Yin X, Liu W, Zhou X, Zhu B, Guo Z, Liu H, Chen X, Feng Y, Tian G, Gao X, Kario K, Cai J*; STEP Study Group.Trial of Intensive Blood-Pressure Control in Older Patients with Hypertension. N EngI J Med.2021;385(14): 1268-1279. (IF=91.245)

5. Song X#, Zou X#, Ge W, Hou C, Cao Z, Zhao H, Zhang T, Jin L, Fu Y, Kong W, Yan C, Cai J*, Wang J*. Blocking FcγRIIB in Smooth Muscle Cells Reduces Hypertension.Circ Rec. 2021;129(2):308-325.(IF=23.213)

6. Jin L#, Shi X, Yang J, Zhao Y, Xue L*, Xu L*, Cai J*.Gut microbes in cardiovascular diseases and their potential therapeutic applications.Protein Cell. 2021;12(5): 346–359.(IF=14.870)

7. Cui C#, Fan J#, Zeng Q#, Cai J#, Chen Y, Chen Z, Wang W, Li SY, Cui Q, Yang J, Tang C, Xu G, Cai J*, Geng B*.CD4+ T-Cell Endogenous Cystathionine γ Lyase-Hydrogen Sulfide Attenuates Hypertension by Sulfhydrating Liver Kinase B1 to Promote T Regulatory Cell Differentiation and Proliferation.Circulation. 2020;142(18):1752-1769.(IF=29.690)

8. Zhou X#, Li J#, Guo J#, Geng B, Ji W, Zhao Q, Li J, Liu X, Liu J, Guo Z, Cai W, Ma Y, Ren D, Miao J, Chen S, Zhang Z, Chen J, Zhong J, Liu W, Zou M, Li Y*, Cai J*. Gut-dependent microbial translocation induces inflammation and cardiovascular events after st-elevation myocardial infarction. Microbiome. 2018;6:66 (IF=10.465)

9. Jin L#, Lin X#, Yang L#, Fan X, Wang W, Li S, Li J, Liu X, Bao M, Cui X, Yang J, Cui Q, Geng B, Cai J*. AK098656, a Novel Vascular Smooth Muscle Cell-Dominant Long Noncoding RNA, Promotes Hypertension.Hypertension.2018; 71(2):262-272.(IF=10.190)

10. Li J#, Zhao F#, Wang Y#, Chen J#, Tao J#, Tian G, Wu S, Liu W, Cui Q, Geng B, Zhang W, Weldon R, Auguste K, Yang L, Liu X, Chen L, Yang X*, Zhu B*, Cai J*.Gut microbiota dysbiosis contributes to the development of hypertension.Microbiome.2017;5(14):66. (IF=9.133, C100)