陳敬洲，研究員，博士研究生導(dǎo)師，協(xié)和學(xué)者特聘教授，準(zhǔn)長(zhǎng)聘系列長(zhǎng)聘副教授，國(guó)家萬(wàn)人計(jì)劃科技創(chuàng)新領(lǐng)軍人才?，F(xiàn)任國(guó)家心血管病中心華中分中心副主任，國(guó)家心血管病中心科研產(chǎn)業(yè)處副處長(zhǎng)，心血管疾病全國(guó)重點(diǎn)實(shí)驗(yàn)室副主任，再生醫(yī)學(xué)重點(diǎn)實(shí)驗(yàn)室副主任，阜外醫(yī)院教育處處長(zhǎng)。
     曾獲茅以升北京青年科技獎(jiǎng)。獲得973課題，國(guó)家自然科學(xué)基金委重點(diǎn)項(xiàng)目，國(guó)家科技重大專項(xiàng)（四大慢病重大專項(xiàng)）課題等項(xiàng)目資助。

長(zhǎng)期從事心腦血管疾病遺傳、環(huán)境危險(xiǎn)因素及其發(fā)病機(jī)制研究，尤其在高血壓腦出血血管病變防控這一中國(guó)特色重大需求而又缺乏關(guān)注的領(lǐng)域，并取得了系列成績(jī)。主要研究?jī)?nèi)容為高血壓靶器官損害，高血壓腦出血管病變機(jī)制及干預(yù)。研究成果在Circulation, iMeta, Nat Commun, Theranostics, Autophagy, Hypertension等權(quán)威期刊發(fā)表。獲省部級(jí)科技獎(jiǎng)5項(xiàng)，國(guó)家發(fā)明專利10項(xiàng)。培養(yǎng)博士、碩士、博士后26余名。任中國(guó)分子心臟病學(xué)雜志（編輯委員會(huì)）副主編 。

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1. Meng Zhang#, Jingyuan Ning#, Jing Liu, Yingying Sun, Ning Xiao, Haochen Xu*, Jingzhou Chen*. Peripheral blood immune landscape and NXPE3 as a novel biomarker for hypertensive intracerebral hemorrhage risk prediction and targeted therapy. iMeta. 2025 Apr 11;4(3):e70030. (IF:33.2)

2. Dongsheng Ni#, Zhaolai Qi#, Shuang Ma#, Yuefeng Wang, Dehuan Liang, Xiyue Zhang, Yong Man, Jingzhou Chen*, Kefei Dou*, Guoping Li*. Membrane-associated ringeCHetype finger 2 protects against metabolic dysfunctionassociated fatty liver disease by targeting fatty acid synthase. Molecular Metabolism. 2025 Jun:96:102137. (IF:6.6)

3. Bai CX#, Su M#, Zhang YH#, Lin YH#,Sun YY,Song L,Xiao N, Xu HC,Wen HY,Zhang M,Ping JD, Liu J,Hui RT,Li H*, Chen JZ*.Oviductal Glycoprotein 1 Promotes Hypertension by Inducing ascular Remodeling Through an Interaction With MYH9.Circulation.2022 Nov ;146(18):1367-1382. (IF:39.918)

4. Chen Z#, Ouyang C#, Zhang H, Gu Y, Deng Y, Du C, Cui C, Li S, Wang W, Kong W, Chen JZ*, Cai J*, Geng B*. Vascular smooth muscle cell-derived hydrogen sulfide promotes atherosclerotic plaque stability via TFEB (transcription factor EB)-mediated autophagy. Autophagy. 2022 Jan 28:1-18. (IF:13.391)

5. Li H#, Xu HC#, Wen HY#, Wang H, Zhao R, Sun YY, Bai CX, Ping JD, Song L, Luo MY*, Chen JZ*. Lysyl hydroxylase 1 (LH1) deficiency promotes angiotensin II (Ang II)-induced dissecting abdominal aortic aneurysm. Theranostics. 2021 Sep 21;11(19):9587-9604. (IF:11.6)

6. Song L#, Li H#, Suo MM, Sun YY, Su M, Song Y, Xiao N, Hui RT, Qin CC*, Chen JZ*. A functional variant of the long noncoding RNA AL110200 is associated with the risk of ischaemic stroke recurrence. Eur J Neurol. 2021 Aug; 28(8): 2708-2715.(IF:6.288)

7. Xiao N#, Liu TL, Li H, Xu HC, Ge J, Wen HY, Bai CX, Song L, Sun YY, Zhang YH, Hui RT, Song WH*, Chen JZ*. Low Serum Uric Acid Levels Promote Hypertensive Intracerebral Hemorrhage by Disrupting the Smooth Muscle Cell-Elastin Contractile Unit and Upregulating the Erk1/2-MMP Axis. Transl Stroke Res. 2020 Oct;11(5):1077-1094. (IF:6.829)

8. Li H#, Xu H#, Li Y#, Jiang Y#, Hu Y, Liu T, Tian X, Zhao X, Zhu Y, Wang S, Zhang C, Ge J, Wang X, Wen H, Bai C, Sun Y, Song L, Zhang Y, Hui R, Cai J, Chen JZ*. Alterations of gut microbiota contribute to the progression of unruptured intracranial aneurysms. Nat Commun. 2020 Jun 25;11(1):3218. (IF:14.919)

9. Liu T#, Wen H#, Li H#, Xu H, Xiao N, Liu R, Chen L, Sun Y, Song L, Bai C, Ge J, Zhang Y, Chen JZ*. Oleic Acid Attenuates Ang II (Angiotensin II)-Induced Cardiac Remodeling by Inhibiting FGF23 (Fibroblast Growth Factor 23) Expression in Mice. Hypertension. 2020 Mar;75(3):680-692. (IF:10.19)

10. Li H#, Xu HC#, Wen HY#, Liu TL, Sun YY, Xiao N, Bai CX, Ge J, Wang XL, Song L, Song Y, Zhang YH, Chen JZ*. Overexpression of LH3 reduces the incidence of hypertensive intracerebral hemorrhage in mice. J Cereb Blood Flow Metab. 2019 Mar;39(3):547-561. (IF:6.04)