岑山，1969年生，籍貫山東濟(jì)南，病毒及抗病毒藥物學(xué)家，醫(yī)藥生物技術(shù)研究所院研究員，博士生導(dǎo)師。1991年獲山東大學(xué)學(xué)士學(xué)位，1994年獲中國(guó)協(xié)和醫(yī)科大學(xué)碩士學(xué)位，1997年獲中國(guó)預(yù)防醫(yī)學(xué)科學(xué)院博士學(xué)位，免疫學(xué)。1998年赴加拿大McGill大學(xué)進(jìn)行博士后研究，開(kāi)展HIV-1研究。2003年起歷任加拿大猶太綜合醫(yī)院研究員，McGill大學(xué)助理教授。2008年起藥生所全職工作，免疫生物學(xué)室主任。

以HIV-1為主的病毒學(xué)基礎(chǔ)研究和抗病毒藥物應(yīng)用研究。側(cè)重于重大和新發(fā)病原病毒（艾滋病病毒、冠狀病毒、流感病毒、手足口、埃博拉等）的病毒宿主相互作用、新型抗感染藥物靶點(diǎn)的發(fā)現(xiàn)以及抗感染新藥研究。

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1. Yi D#, Li Q#, Wang H#, Ma L#, Wang Y, Lv K, Chen S, Wang J, Zhang Y, Liu Z, Liu M, Shi Y*, Gao G, Cen S*. Repurposing of Berbamine Hydrochloride to Inhibit Ebola Virus by Targeting Viral Glycoprotein. Acta Pharmaceutica Sinica B (Accepted) (IF= 14.903)

2. Ding J#, Wang S#, Wang Z, Chen S, Zhao J, Solomon M, Liu Z, Guo F, Ma L, Wen J, Li X*, Liang C*, Cen S*. Schlafen 5 Suppresses Human Immunodeficiency Virus Type 1 Transcription by Commandeering Cellular Epigenetic Machinery. Nucleic Acids Res. 2022:gkac489. (IF= 19.160)

3. Zhao J#, Wang J#, Pang X#, Liu Z, Li Q, Yi D, Zhang Y, Fang X, Zhang T, Zhou R, Zhang T, Guo Z, Liu W, Li X, Liang C, Deng T, Guo F*, Yu L*, Cen S*. Microbial metabolites function as a PROTAC to degrade influenza A virus PA. Nat Commun. (2022) 13:2079. (IF= 17.694)

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5. Zhao J#, Liu Q#, Yi D, Li Q, Guo S, Ma L, Zhang Y, Dong D, Guo F, Liu Z, Wei T*, Li X*, Cen S*. 5-Iodotubercidin Inhibits SARS-CoV-2 RNA Synthesis. Antiviral Res. 2022 Jan 28;198:105254. (IF= 10.103)

6. Zhao J#, Guo S#, Yi D#, Li Q, Ma L, Zhang Y, Wang J, Li X, Guo F, Lin R, Liang C, Liu Z*, Cen S*. A cell-based assay to discover inhibitors of SARS-CoV-2 RNA dependent RNA polymerase. Antiviral Res. 2021;190:105078. (IF= 10.103)

7. Li Q^#, Yi D^#, Lei X^#, Zhao J, Zhang Y, Cui X, Xiao X, Jiao T, Dong X, Zhao X, Zeng H, Liang C, Ren L, Guo F, Li X, Wang J*, Cen S*. Corilagin inhibits SARS-CoV-2 viral replication by targeting the RNA-dependent RNA polymerase. Acta Pharm Sin B. 2021 Feb 15. (IF= 11.413)

8. Wang J#, Zhang Y#, Li Q, Zhao J, Yi D, Ding J, Zhao F, Hu S, Zhou J, Deng T, Li X*, Guo F, Liang C, Cen S*.. Influenza virus exploits an interferon-independent lncRNA to warrant viral RNA synthesis by suppression of RIG-I mediated immune response. Cell reports. 2019 Jun 11;27(11):3295-3304. (IF= 8.109)

9. Zhang Y#, Huang Y#, Li Q#, Li X, Zhou Y, Guo F, Zhou J*, Cen S*. A highly conserved amino acid in VP1regulatesmaturation of enterovirus 71. Plos Pathogens. 2017 Sep 22;13(9):e1006625. doi: 10.1371 (IF= 6.608)

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