趙春華，醫(yī)學博士、博士生導師。國際衰老和疾病協(xié)會主席。北京協(xié)和醫(yī)學院長聘教授，中國醫(yī)學科學院組織工程研究中心主任，干細胞新藥研發(fā)及臨床轉化研究北京市重點實驗室主任。致力于干細胞生物學、藥學與臨床研究30余年，國家973計劃、863計劃、國家重點研發(fā)計劃等項目首席科學家，國際上提出了“亞全能干細胞學說”概念和“間充質干細胞系統(tǒng)”概念，建立了集成體干細胞基礎理論、關鍵科學技術、臨床試驗治療研究為一轉化醫(yī)學體系。

致力于干細胞生物學、藥學與臨床研究30余年，國際上提出了“亞全能干細胞學說”概念和“間充質干細胞系統(tǒng)”概念，獲國家藥監(jiān)局（SFDA）首個干細胞新藥臨床批件，實踐了干細胞新制品臨床安全有效治療疾病。建立了集成體干細胞基礎理論、關鍵科學技術、臨床試驗治療研究為一轉化醫(yī)學體系。

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1. Pei Wang#, Longfei Tang , Bohui Zhou , Liangfen Cheng , Robert Chunhua Zhao*，Juan Zhang*.Analytical methods for the detection of PD-1/PD-L1 and other molecules related to immune checkpoints.Trends in Analytical Chemistry, 146 (2022) 116505. (IF=14.9)

2. Li X #, Sun Z #, Peng G #, Xiao Y, Guo J, Wu B, Li X, Zhou W, Li J, Li Z, Bai C, Zhao L*, Han Q*, Robert Chunhua Zhao*, Wang X*. Single-cell RNA sequencing reveals a pro-invasive cancer-associated fibroblast subgroup associated with poor clinical outcomes in patients with gastric cancer.Theranostics. 2022 Jan 1;12(2):620-638. (IF=11.556)

3. Zhu R#, Yan T#, Feng Y#, Liu Y#, Cao H, Peng G, Yang Y, Xu Z, Liu J, Hou W, Wang X, Li Z, Deng L, Wang S, Li J, Han Q, Li H, Shan G, Cao Y, An X, Yan J, Zhang Z, Li H, Qu X, Zhu J, Zhou S, Wang J, Zhang F, Gao J, Jin R*, Xu D, Ma YQ, Huang T, Peng S, Zheng Z, Stambler I, Gilson E, Lim LW, Moskalev A, Cano A, Chakrabarti S, Ulfhake B, Su H, Xu H, Xu S, Wei F, Brown-Borg HM, Min KJ, Ellison-Hughes G, Caruso C, Jin K*, Zhao RC*. Mesenchymal stem cell treatment improves outcome of COVID19 patients via multiple immunomodulatory mechanisms. Cell Res. 2021 Oct 26:1-19. (IF=46.2953)

4. Xian Xiao#, Meiqian Xu, Hongliang Yu, Liping Wang, Xiaoxia Li, Janusz Rak, Shihua Wang* and Robert Chunhua Zhao*. Mesenchymal stem cell derived small extracellular vesicles mitigate oxidative stress-induced senescence in endothelial cells via regulation of miR-146a/Src signal transduction and targeted therapy. Signal Transduct Target Ther. 2021 Oct 22;6(1):354. (IF= 38.1027)

5. Leng Z#, Zhu R#, Hou W#, Feng Y#, Yang Y, Han Q, Shan G, Meng F, Du D, Wang S, Fan J, Wang W, Deng L, Shi H, Li H, Hu Z, Zhang F, Gao J, Liu H*, Li X, Zhao Y, Yin K, He X, Gao Z, Wang Y, Yang B, Jin R*, Stambler I, Lim LW, Su H, Moskalev A, Cano A, Chakrabarti S, Min KJ, Ellison-Hughes G, Caruso C, Jin K*, Zhao RC*. Transplantation of ACE2- Mesenchymal Stem Cells Improves the Outcome of Patients with COVID-19 Pneumonia. Aging Dis. 2020 April: 11(2):216-228. (IF=9.9675, ESI, C100, R)

6. Li J#, Hao Y#, Mao W#, Xue X#, Xu P, Liu L, Yuan J, Zhang D, Li N, Chen H, Zhao L, Sun Z*, Luo J*, Chen R*, Zhao RC*.LincK contributes to breast tumorigenesis by promoting proliferation and epithelial-to-mesenchymal transition.J Hematol Oncol. 2019 Feb 22;12(1):19. (IF=11.059)

7. Xingxia Liu#, Xuebin Qu, Yuan Chen, Lianming Liao, Kai Cheng, Changshun Shao, Martin Zenke, Armand Keating, Robert C H Zhao*. Mesenchymal stem/stromal cells induce the generation of novel IL-10-dependent regulatory dendritic cells by SOCS3 activation. J Immunol. 2012 Aug 1;189(3):1182-92. (IF=5.5199, F1000)

8. Zhang B#, Liu R, Shi D, Liu X, Chen Y, Dou X, Zhu X, Lu C, Liang W, Liao L, Zenke M*, Robert C H Zhao*. Mesenchymal stem cells induce mature dendritic cells into a novel Jagged-2 dependent regulatory dendritic cell population. Blood. 2009 Jan 1;113(1):46-57. (IF=10.558, C100)

9. Qiao L#, Xu Z, Zhao T, Zhao Z, Shi M, Zhao RC*, Ye L*, Zhang X*. Suppression of tumorigenesis by human mesenchymal stem cells in a hepatoma model. Cell Res. 2008 Apr;18(4):500-7. (IF=9.417, C100)

10. Fang B#, Zheng C#, Liao L, Han Q, Sun Z, Jiang X, Zhao RC*. Identification of human chronic myelogenous leukemia progenitor cells with hemangioblastic characteristics. Blood. 2005 Apr 1;105(7):2733-40. (IF=10.558)