楊勇，長聘教授，主任醫(yī)師，博士研究生導(dǎo)師，中國醫(yī)學(xué)科學(xué)院皮膚病醫(yī)院副院所長，江蘇省皮膚醫(yī)學(xué)重點(diǎn)實(shí)驗(yàn)室主任。曾獲北京市科學(xué)技術(shù)獎(jiǎng)（2009和2016，均為第一完成人），第六屆國之名醫(yī)·優(yōu)秀風(fēng)范獎(jiǎng)（2023）。獲得國家杰出青年科學(xué)基金和國自然重點(diǎn)項(xiàng)目（2018，2021和2023）等資助。 院校引進(jìn)人才，2018年加入院校，曾在北京大學(xué)第一醫(yī)院任主任醫(yī)師。

長期從事遺傳性皮膚病、離子通道病、疼痛及瘙癢的研究，帶領(lǐng)課題組首次探明7種遺傳病的致病基因和發(fā)病機(jī)制，其中4種是離子通道病，首次提出皮膚離子通道病的概念，揭示了兩種與疼痛和瘙癢密切相關(guān)的離子通道。先后主持8項(xiàng)國家自然科學(xué)基金，包括國家杰出青年科學(xué)基金（2014），國自然重點(diǎn)項(xiàng)目（2017，2021和2023）等。已發(fā)表SCI論文70余篇，被他引千余次，部分成果系列發(fā)表于Nat Genet，Nat Chem Biol，Am J Hum Genet，J Clin Invest等雜志。

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1. Chen Z*#, Liu Y, Yu H, Li J, Huang X, Xiang R, Mo R, Chen H*, Yang Y*. Safety and efficacy of topical simvastatin plus cholesterol cream versus topical simvastatin cream alone for porokeratosis ptychotropica: A randomized, single-blind, split-body, placebo-controlled, investigator-initiated trial. J Am Acad Dermatol. 2025 Oct;93(4):980-987. (IF=11.8)

2. Xu F#, Cui YZ, Yang XY, Zheng YX, Chen XB, Zhou H, Wang ZY, Zhou Y, Lu Y, Li YY, Ye LR, Fu NC, Chen SQ, Chen XY, Zheng M, Yang Y*, Man XY*. CXCL10 secreted by SPRY1-deficient epidermal keratinocytes fuels joint inflammation in psoriatic arthritis via CD14 signaling. J Clin Invest. 2025 Jun 5;135(15):e186135. (IF=13.6)

3. Fan J#, Hu L#, Yue Z#, Liao D#, Guo F, Ke H, Jiang D*, Yang Y*, Lei X*. Structural basis of TRPV3 inhibition by an antagonist. Nat Chem Biol. 2023 Jan;19(1):81-90. (IF=13.0)

4. Zhao J#, Munanairi A#, Liu XY, Zhang J, Hu L, Hu M, Bu D, Liu L, Xie Z, Kim BS, Yang Y*, Chen ZF*. PAR2 Mediates Itch via TRPV3 Signaling in Keratinocytes. J Invest Dermatol. 2020 Aug;140(8):1524-1532. (IF=8.551)

5. Lin Z#, Li S, Feng C, Yang S, Wang H, Ma D, Zhang J, Gou M, Bu D, Zhang T, Kong X, Wang X, Sarig O, Ren Y, Dai L, Liu H, Zhang J, Li F, Hu Y, Padalon-Brauch G, Vodo D, Zhou F, Chen T, Deng H, Sprecher E, Yang Y*, Tan X*. Stabilizing mutations of KLHL24 ubiquitin ligase cause loss of keratin 14 and human skin fragility. Nat Genet. 2016 Dec;48(12):1508-1516. (IF=27.959, C100)

6. Lin Z#, Zhao J#, Nitoiu D#, Scott CA#, Plagnol V, Smith FJ, Wilson NJ, Cole C, Schwartz ME, McLean WH, Wang H, Feng C, Duo L, Zhou EY, Ren Y, Dai L, Chen Y, Zhang J, Xu X, O'Toole EA, Kelsell DP*, Yang Y*. Loss-of-function mutations in CAST cause peeling skin, leukonychia, acral punctate keratoses, cheilitis, and knuckle pads. Am J Hum Genet. 2015 Mar 5;96(3):440-447. (IF=10.794)

7. Lin Z#, Chen Q#, Shi L, Lee M, Giehl KA, Tang Z, Wang H, Zhang J, Yin J, Wu L, Xiao R, Liu X, Dai L, Zhu X, Li R, Betz RC, Zhang X*, Yang Y*. Loss-of-function mutations in HOXC13 cause pure hair and nail ectodermal dysplasia. Am J Hum Genet. 2012 Nov 2;91(5):906-911. (IF=11.202)

8. Lin Z#, Chen Q#, Lee M#, Cao X#, Zhang J, Ma D, Chen L, Hu X, Wang H, Wang X, Zhang P, Liu X, Guan L, Tang Y, Yang H, Tu P, Bu D, Zhu X, Wang K, Li R*, Yang Y*. Exome sequencing reveals mutations in TRPV3 as a cause of Olmsted syndrome. Am J Hum Genet. 2012;90(3):558-564. (IF=11.202, C100)

9. Han C#, Rush AM, Dib-Hajj SD, Li S, Xu Z, Wang Y, Tyrrell L, Wang X, Yang Y*, Waxman SG*. Sporadic onset of erythermalgia: a gain-of-function mutation in Nav1.7. Ann Neurol. 2006 Mar;59(3):553-558. (IF=8.051, C100)

10. Yang Y#, Wang Y#, Li S#, Xu Z, Li H, Ma L, Fan J, Bu D, Liu B, Fan Z, Wu G, Jin J, Ding B, Zhu X*, Shen Y*. Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia. J Med Genet. 2004 Mar;41(3):171-174. (IF=4.112, C100)