宋偉，1979年出生，籍貫河北任丘，中國醫(yī)學(xué)科學(xué)院基礎(chǔ)醫(yī)學(xué)研究所研究員，博士生導(dǎo)師。1998年考入內(nèi)蒙古科技大學(xué)預(yù)防醫(yī)學(xué)專業(yè)，2003年獲得學(xué)士學(xué)位。2003年在河北醫(yī)科大學(xué)生物化學(xué)與分子生物學(xué)專業(yè)攻讀碩士學(xué)位，從事心血管分子生物學(xué)研究。2006年在北京協(xié)和醫(yī)學(xué)院生物化學(xué)與分子生物學(xué)專業(yè)攻讀博士學(xué)位，從事雄性生殖發(fā)育研究。2009年畢業(yè)留校工作，同年升為助理研究員。2014年升為副研究員。2020年升為研究員。

本人長期致力于雄性生殖發(fā)育及相關(guān)重大疾病（不育與腫瘤）的分子機(jī)理與轉(zhuǎn)化應(yīng)用研究。主要研究內(nèi)容：1）精原干細(xì)胞穩(wěn)態(tài)與再生的調(diào)控機(jī)理研究；2）睪丸微環(huán)境調(diào)控生精細(xì)胞發(fā)育的機(jī)理研究；3）雄性生精障礙的分子機(jī)理與基因治療研究；4）腫瘤微環(huán)境的分子調(diào)控機(jī)理與轉(zhuǎn)化應(yīng)用研究。 目前在Adv. Sci、 Dev Cell、Theranostics、Gut、Sci Adv、eLife、Genome Res、Cell Res、Nat. Commun、STTT等雜志發(fā)表研究論文40多篇。申請(qǐng)國家發(fā)明專利17項(xiàng)和PCT國際專利1項(xiàng)，已獲得專利授權(quán)14項(xiàng)。申請(qǐng)并獲批團(tuán)標(biāo)2項(xiàng)，專家共識(shí)1項(xiàng)。

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1. Pengyu Li#; Zexuan Zhang; Zihan Xie; Cheng Jin; Zhipeng Wang; Jielin Tang;  Mengzhen Li; Dingfeng Zou; Xinyu Mang; Jun Liu; Dingyao Chen; Qi Geng; Jun Zhu; Yan Lu; Changwei Yuan; Ning Zhang; Shiying Miao; Jing Peng*; Kai Li*; Wei Song*. IL1R2 Marks and Sorts a Spermatogonial Stem Cell Population Critical for Restoring Spermatogenesis Upon Interruption in Mammals.  2025, （IF=13.638）

2. Dingfeng Zou#; Kai Li#; Luying Su#; Jun Liu; Yan Lu; Rong Huang; Mengzhen Li; Xinyu Mang; Qi Geng; Pengyu Li; Jielin Tang; Zhixin Yu; Zexuan Zhang; Dingyao Chen; Shiying Miao; Jia Yu*; Wei Yan*; Wei Song*. DDX20 is required for cell cycle reentry of prospermatogonia and establishment of spermatogonial stem cell pool during testicular development in mice, Dev. Cell 2024,59(13):1707-1723.（IF=8.7）

3. Qian Zhaoyang#; Liang Junbo#; Huang Rong#; Song Wei#; Ying Jianming*; Bi Xinyu; Zhao Jianjun; Shi Zhenyu; Liu Wenjie; Liu Jianmei; Li Zhiyu; Zhou Jianguo; Huang Zhen; Zhang Yefan; Zhao Dongbing; Wu Jianxiong; Wang Liming; Chen Xiao; Mao Rui; Zhou Yanchi; Guo Lei; Hu Hanjie; Ge Dazhuang; Li Xingchen; Luo Zhiwen; Yao Jinjie; Li Tengyan; Chen Qichen; Wang Bingzhi; Wei Zhewen; Chen Kun; Qu Chunfeng; Cai Jianqiang*; Jiao Yuchen*; Bao Li*; Zhao Hong*. HBV integrations reshaping genomic structures promote hepatocellular carcinoma, Gut, 2024, 2023(330414): 1-14.（IF=25.8）

4. Cheng Jin#, Zhipeng Wang#, Pengyu Li, Jielin Tang, Tao Jiao, Yiran Li, Jinhuan Ou, Dingfeng Zou, Mengzhen Li, Xinyu Mang, Jun Liu, Yanni Ma, Xiaolong Wu, Jie Shi, Shitao Chen, Manman He, Yan Lu, Ning Zhang, Shiying Miao, Fei Sun, Linfang Wang, Kai Li*, Jia Yu*, Wei Song*. Decoding the spermatogonial stem cell niche under physiological and recovery conditions in adult mice and humans. Sci. Adv 2023, 3173:1-17. (IF=13.6)

5. Zhipeng Wang#, Cheng Jin#, Pengyu Li, Yiran Li, Jielin Tang, Zhixin Yu, Tao Jiao, Jinhuan Ou, Han Wang, Dingfeng Zou, Mengzhen Li , Xinyu Mang, Jun Liu, Yan Lu, Kai Li, Ning Zhang, Jia Yu, Shiying Miao, Linfang Wang, Wei Song*. Identiffcation of quiescent FOXC2+ spermatogonial stem cells in adult mammals. ELife 2023, 12:1-22. (IF=7.7)

6. Yalan Lu#, Rong Huang#, jianming Ying#, Xingchen Li#, Tao Jiao, Lei Guo, Haitao Zhou, Han Wang, Amannisa Tuersuntuonebit, Jianmei Liu, Qichen Chen, Yanhong Wang, Luying Su, Changyuan Guo, Fu Xu, Ziyi Wang, Yan Lu, Kai Li, Junbo Liang, Zhen Huang, Xiao Chen, Jinjie Yao, Hanjie Hu, Xiaowen Cheng, Yufeng Wan, Xinyan Chen, Ning Zhang, Shiying Miao, Jianqiang Cai, Linfang Wang, Changzheng Liu*, Wei Song*, Hong Zhao*. RING finger 138 deregulation distorts NF-кB signaling and facilities colitis switch to aggressive malignancy. STTT 2022, 13;7(1):185. (IF=39.3)

7. Kai Li#, Jiayue Xu#, Yanyun Luo#, Dingfeng Zou, Ruiqin Han, Shunshun Zhong, Qing Zhao, Xinyu Mang, Mengzhen Li, Yanmin Si,  Yan Lu, Pengyu Li, Cheng Jin, Zhipeng Wang, Fang Wang, Shiying Miao, Bo Wen, Linfang Wang, Yanni Ma*, Jia Yu*, Wei Song*. Panoramic transcriptome analysis and functional screening of long non-coding RNAs in mouse spermatogenesis. GENOME RES 2021, 31(1):13-26. (IF=9.438)

8. Shangze Li#*, Qipeng Shu, Yang Song, Hui-Hui Zhang, Yi Liu, Bingxue Jin, Tianzi Liuyu, Chao Li, Xichen Huang, Runlei Du, Wei Song*, Bo Zhong*, Xiaodong Zhang*. Phosphorylation of MAVS/VISA by Nemo-like kinase (NLK) for degradation regulates the antiviral innate immune response. Nat. Commun 2019, 10: 3233. (IF= 11.878)

9. Fang Wang#, Wei Song#, Hongmei Zhao, Yanni Ma, Yuxia Li, Di Zhai, Jingnan Pi, Yanmin Si, Jiayue Xu, Lei Dong, Rui Su, Mengmeng Zhang, Yong Zhu, Xiaoxia Ren, Fei Miao, Wenjie Liu, Feng Li, Junwu Zhang, Aibin He, Ge Shan, Jingyi Hui, Linfang Wang, Jia Yu*. The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis. Cell Res 2017, 27(3): 416-439. (IF=15.606)

10.Wei Song#, Wenjie Liu#, Hong Zhao, Shangze Li, Xin Guan, Jianming Ying, Yefan Zhang, Fei Miao, Mengmeng Zhang, Xiaoxia Ren, Xiaolu Li, Fan Wu, Yuechao Zhao, Yuanyuan Tian, Wenming Wu, Jun Fu, Junbo Liang, Wei Wu, Jia Yu, Shudong Zong, Shiying Miao, Xiaodong Zhang*, Linfang Wang*. Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signaling pathway. Nat. Commun 2015, 6: 8022. (IF= 11.3285)