楊沛然，博士生導師，本科、碩士、博士均畢業(yè)于英國劍橋大學，曾在美國哈佛醫(yī)學院進行研究工作，開展肺動脈高壓First-in-class新藥研究并推動其轉化，曾獲得英國藥理學會獎項。
      院校引進人才，2021年加入中國醫(yī)學科學院基礎醫(yī)學研究所，呼吸和共病全國重點實驗室，主持國家級青年人才項目、國家科技重大專項青年科學家項目、國家自然科學基金項目等。

楊沛然博士的研究方向是聚焦肺血管病變的呼吸疾病和共病研究，基于臨床隊列研究，結合多組學技術和特色體內外模型，解析不同類型肺動脈高壓和呼吸共病的發(fā)生發(fā)展機制，探究肺血管病變在多種呼吸疾病中的作用，挖掘治療靶點并開發(fā)新型療法。作為第一或共同通訊作者（含共同）在Circulation, Sci Transl Med, Lancet RHWP等雜志發(fā)表論文，共發(fā)表SCI論文70余篇，被引2600余次，研究成果納入相關領域指南。

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1．Wang Y, Guo Z, Ma X, Xu Q, Li D, Yang J, Lu X, Yang P*, Zhang H*, Zhao H*, Wang C*. Integrated transcriptome and metabolome analysis reveals the therapeutic mechanism of Huang-Qi-Si-Wu-Tang in experimental pulmonary arterial hypertension. Phytomedicine. 2025 145:157058.

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6．Chen Y, Song M, Li Z, Hou L, Zhang H, Zhang Z, Hu H, Jiang X, Yang J, Zou X, Pang J, Zhang T, Yang P*, Wang J*, Wang C*. FcεRI deficiency alleviates silica-induced pulmonary inflammation and fibrosis. Ecotoxicol Environ Saf. 2022 244:114043.

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