劉洋，研究員，博士研究生導(dǎo)師，獨(dú)立課題組長(zhǎng)。北京協(xié)和醫(yī)學(xué)院醫(yī)學(xué)博士學(xué)位，牛津大學(xué)訪問學(xué)者。獲得國(guó)家優(yōu)秀青年科學(xué)基金、國(guó)自然面上、北自然面上、北京市科技新星計(jì)劃等項(xiàng)目資助。入選《麻省理工科技評(píng)論》亞太區(qū)“35歲以下科技創(chuàng)新35人”、中國(guó)科協(xié)“青年人才托舉工程”，被中共北京市委、北京市人民政府授予“北京市優(yōu)秀青年人才”稱號(hào)，應(yīng)邀參加“第68屆諾貝爾獎(jiǎng)醫(yī)學(xué)/生理學(xué)獲得者大會(huì)”。
      院校引進(jìn)人才，2019年8月加入院校。

長(zhǎng)期從事天然免疫、腫瘤免疫方向的研究。發(fā)現(xiàn)抗病毒天然免疫的“表觀-代謝”協(xié)同調(diào)控新機(jī)制、感染性疾病診治新靶標(biāo)，從RNA表觀遺傳修飾層面揭示了抗菌天然免疫應(yīng)答新模式、炎癥疾病發(fā)病新機(jī)理，在國(guó)際上率先提出“腫瘤轉(zhuǎn)移前微環(huán)境PMN的六大特征”新概念。相關(guān)成果以獨(dú)立一作和/或通訊作者在Science、Cancer Cell和Signal Transduct Target Ther等期刊發(fā)表系列文章，以第一發(fā)明人授權(quán)國(guó)家發(fā)明專利3項(xiàng)。

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1. Yang Liu#^,*, Xuetao Cao*. Cellular RNA acts as an antiviral MAVS signalosome scaffold. Trends Immunol. 2025; 46(2):97-99. (IF=13.9)

2. Yang Liu#^,*, Renjie Song, Zhike Lu, Lu Zhao, Xinyi Zhan, Yini Li and Xuetao Cao. The RNA m⁶A demethylase ALKBH5 drives emergency granulopoiesis and neutrophil mobilization by upregulating G-CSFR expression. Cell Mol Immunol. 2024; 21(1):6-18. (IF=19.8)

3. Lu Zhao#, Renjie Song, Yang Liu*. Glycolytic metabolite phosphoenolpyruvate protects host from viral infection through promoting AATK expression. Eur J Immunol. 2023; 53(12): e2350536.  (IF=5.4)

4. Yang Liu#^,*, Renjie Song, Lu Zhao, Zhike Lu, Yini Li, Xinyi Zhan, Fengjiao Lu, Jiang Yang, Yamei Niu, Xuetao Cao*. m⁶A demethylase ALKBH5 is required for antibacterial innate defense by intrinsic motivation of neutrophil migration. Signal Transduct Target Ther. 2022; 7(1):194.  (IF=39.3)

5. Panpan Li#, Yang Liu#^,*, Renjie Song, Lu Zhao, Jiang Yang, Fengjiao Lu, Xuetao Cao*. RNA 2'-O-Methyltransferase Fibrillarin facilitates virus entry into macrophages through inhibiting type I interferon response. Front Immunol. 2022; 13:793582. (IF=7.3)

6. Yang Liu#, Yuling You, Zhike Lu, Jiang Yang, Panpan Li, Lun Liu, Henan Xu, Yamei Niu, Xuetao Cao*. N⁶-methyladenosine RNA modification-mediated cellular metabolism rewiring inhibits viral replication. Science. 2019; 365(6458):1171-1176.  (IF=41.8, C100)

7. Yang Liu#, Xuetao Cao*. Characteristics and significance of the pre-metastatic niche. Cancer Cell. 2016; 30(5):668-681.  (IF=27.4, ESI)

8. Yang Liu#, Xuetao Cao*. Organotropic metastasis: role of tumor exosomes. Cell Res. 2016; 26(2):149-150.  (IF=15.6)

9. Yang Liu#, Xuetao Cao*. Immunosuppressive cells in tumor immune escape and metastasis. J Mol Med. 2016; 94(5):509-522.  (IF=4.7, ESI)

10. Yang Liu#, Xuetao Cao*. Intratumoral dendritic cells in the anti-tumor immune response. Cell Mol Immunol. 2015; 12(4):387-390.  (IF=5.2)