王琳，研究員、準聘助理教授、博士生導師。2015年畢業(yè)于浙江大學獲理學博士學位。2022年獲國家級人才項目資助，承擔國自然青年項目、面上項目、重點研發(fā)青年科學家項目、北京市重點項目等。
      院校引進人才，2021年底回國加入基礎所。曾于2017年加入美國普林斯頓大學進行博士后研究。

研究領域為新代謝物及其功能的創(chuàng)新研究:(1)融合組合化學合成策略和生物信息學分析，構建新代謝物數據庫，挖掘其與復雜生理、病理狀態(tài)的分子關聯(lián);(2)基于自主研發(fā)的空間分辨代謝成像體系，全面解析新代謝物在體內的精準分布及細胞特異性定位，揭示其在生理和病理狀態(tài)下的原位特征;(3)整合活體代謝流示蹤與機器學習算法，系統(tǒng)剖析新代謝物在疾病發(fā)生發(fā)展中的關鍵調控網絡與分子機制，探索其作為新一代精準治療靶點的轉化潛力。

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1. Yue Li#, Jiaxuan Cao#, Jingyuan Tong#, Peixia Tang#, Hanran Chen, Guohuan Sun, Zining Yang, Xiaoru Zhang, Fang Dong, Shangda Yang, Jie Gao, Xiangnan Zhao, Jinfa Ma, Di Wang, Lei Zhang, Lin Wang*, Tao Cheng*, Hui Cheng*, Lihong Shi*. Leukemia-expanded splenic CD81+ erythroblasts potentiate disease progression by reshaping leukemic cell metabolism. Journal of Clinical Investigations. 2025, in-press. (IF=13.3)

2. Hong Deng#, Huimin Wang, Yiyi Zhang,  Runmeng Liu, Wei Hou, Lin Wang*, Haiyan Xu*, Weiqi Zhang*. Tumor associated macrophage mediated delivery of nano-photosensitizer enables light-induced metabolic programming for immuno-photodynamic therapy. Protein & Cells. 2025, doi: 10.1093/procel/pwaf064. (IF=13.6)

3. Yinghao Cao#, Shengxi Li, Zhaoyi Liu, Zixian Jia, Weidong Zhuang, Xu Pan, Jinyu Zhou, Lifeng Yang*, Lin Wang*. SMART: an approach for accurate formula assignment in spatially resolved metabolomics. Analytical Chemistry. 2025, 97(29), 15570-15578. (IF=7.4)

4. Shilin Xu#, Tao Wang, Xuechun Hu, Hong Deng, Yiyi Zhang, Lei Xu, Yang Zeng, Jia Yu, Weiqi Zhang*, Lin Wang*, Haiyan Xu*. A dual chemodrug-loaded hyaluronan nanogel for differentiation induction therapy of refractory AML via disrupting lysosomal homeostasis. Science Advances. 2025, 11(13), 3923-3939. (IF=11.7)

5. Lin Wang#, Xi Xing, Xianfeng Zeng, S. RaElle Jackson, Tara TeSlaa, Osama AI-Dalahmah, Laith Z Samarah, Katharine Goodwin, Lifeng Yang, Melanie R McReynolds, Xiaoxuan Li, Jeremy J Wolff, Joshua D Rabinowitz*, Shawn M Davidson*. Spatially resolved isotope tracing  reveals tissue  metabolic activity. Nature Methods, 2022, 19(2), 223-230. (IF=31.1)