王芳，教授，博士研究生導(dǎo)師，1983年出生，籍貫山東。2004年本科畢業(yè)于山東大學(xué)生物技術(shù)專業(yè)，同年進(jìn)入醫(yī)科院基礎(chǔ)所攻讀博士研究生，2009年獲博士學(xué)位后，留所工作至今。2012年晉升副教授，2017年晉升教授，并于2023年獲得準(zhǔn)聘助理研究員資格。獲科技部重點(diǎn)研發(fā)計(jì)劃（青年科學(xué)家項(xiàng)目）”、國家“優(yōu)秀青年科學(xué)基金”、醫(yī)科院“青年醫(yī)學(xué)人才獎(jiǎng)勵(lì)項(xiàng)目”、“協(xié)和新星” 等人才計(jì)劃支持。作為第三完成人，獲教育部自然科學(xué)二等獎(jiǎng)。

長期從事RNA調(diào)控與造血發(fā)育及疾病研究。通過RNA研究相關(guān)技術(shù)的開發(fā)，解析造血干細(xì)胞發(fā)育、分化及血液系統(tǒng)相關(guān)疾病發(fā)生發(fā)展的基本規(guī)律；以期為血細(xì)胞再生和血液系統(tǒng)疾病臨床診治提供理論基礎(chǔ)和新方向。承擔(dān)多個(gè)國家級(jí)科研項(xiàng)目，在Nat. Cell Biol、Cell Res、Nat. Commun等雜志發(fā)表論文20余篇。

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1.Hui Wang#, Zhaoru Zhang#, Chenxi Han#, Penglei Jiang#, Jiayue Xu#, Yingli Han#, Deyu Huang, Jian Li, Jie Zhou, Michael Durnin, Shiyuan Chen, Yaxin Liu, Jinghao Sheng, Jie Cao, Jianzhao Liu, Bing Liu*, Jia Yu*, Fang Wang*, Pengxu Qian*. SNORD113-114 cluster maintains haematopoietic stem cell self-renewal via orchestrating the translation machinery. Nat Cell Biol. 2025 Feb;27(2):246-261. （IF=19.5）

2. Weiqian Li#, Yue Huo#, Yue Ren#, Chenxi Han, Shuo Li, Kangning Wang , Manman He, Yiying Chen, Yanran Wang, Lingjie Xu, Yuehong Guo, Yanmin Si, Yufeng Gao, Jiayue Xu, Xiaoshuang Wang, Yanni Ma, Jia Yu*, Fang Wang*. Deciphering the Functional Long Non-Coding RNAs Derived from MicroRNA Loci. Adv. Sci. 2023 Nov;10(33):e2203987. (IF=14.3)

3. You Q#, Wang F#, Du R, Pi J, Wang H, Huo Y, Liu J, Wang C, Yu J*, Yang Y*, Zhu L*. m6A Reader YTHDF1-Targeting Engineered Small Extracellular Vesicles for Gastric Cancer Therapy via Epigenetic and Immune Regulation. Adv Mater. 2023 Feb;35(8):e2204910. (IF=27.4)

4. Xueju Wei#, Yue Huo#, Jingnan Pi#, Yufeng Gao#, Shuan Rao#, Manman He, Qinglv Wei, Peng Song, Yiying Chen, Dongxu Lu, Wei Song, Junbo Liang, lingjie Xu, Haixia Wang, Guolin Hong, Yuehong Guo, Yanmin Si, Jiayue Xu, Xiaoshuang Wang, Yanni Ma, Shuyang Yu, Dongling Zou, Jing Jin*, Fang Wang*, Jia Yu*. METTL3 preferentially enhances non-m6A translation of epigenetic factors and promotes tumorigenesis. Nat Cell Biol. 2022 Aug;24(8):1278-1290. (IF=21.3，C100)

5. Fang Wang#, Puwen Tan#, Pengcheng Zhang#, Yue Ren#, Jie Zhou, Yunqiao Li, Siyuan Hou, Shuaili Li, Linlin Zhang, Yanni Ma, Chaojie Wang, Wanbo Tang, Xiaoshuang Wang, Yue Huo, Yongfei Hu, Tianyu Cui, Chao Niu, Dong Wang*, Bing Liu*, Yu Lan*, Jia Yu*. Single-cell architecture and functional requirement of alternative splicing during hematopoietic stem cell formation. Sci Adv. 2022 Jan 7;8(1):eabg5369. (IF=13.6)

6. Ren Y#, Huo Y#, Li W#, He M, Liu S, Yang J, Zhao H, Xu L, Guo Y, Si Y, Zhao H, Rao S, Wang J, Ma Y, Wang X*, Yu J*, Wang F*. A global screening identifies chromatin-enriched RNA-binding proteins and the transcriptional regulatory activity of QKI5 during monocytic differentiation. Genome Biol. 2021 Oct 14;22(1):290. (IF=18)

7. Pi J#, Wang W#, Ji M, Wang X, Wei X, Jin J, Liu T, Qiang J, Qi Z, Li F, Liu Y, Ma Y, Si Y, Huo Y, Gao Y, Chen Y, Dong L, Su R, Chen J, Rao S, Yi P, Yu S, Wang F*, Yu J*. YTHDF1 Promotes Gastric Carcinogenesis by Controlling Translation of FZD7. Cancer Res. 2021, 81(10):2651-2665. (IF=13.3, ESI)

8. Yan Huang#, Puwen Tan#, Xiaoshuang Wang, Ying Yi, Yongfei Hu, Dong Wang*, Fang Wang*. Transcriptomi c insights into temporal expression pattern of autophage genes during monocytic and granulocytic differentiation. Autophagy. 2018, 14(3): 558-559. (IF=11.1)

9.Fang Wang#, Wei Song#, Hongmei Zhao#, Yanni Ma, Yu xia Li, Di Zhai, Jingnan Pi, Yanmin Si, Jiayue Xu, Lei Dong, Rui Su, Mengmeng Zhang, Yong Zhu, Xiaoxia Ren, Fei Miao, Wenjie Liu, Feng Li, Junwu Zhang, Aibin He, Ge Shan, Jingyi Hui, Linfang Wang, Jia Yu*. The RNA-binding protein QKI5 regulates primary miR-124-1 processing via a distal RNA motif during erythropoiesis. Cell Res. 2017, 27(3): 416-439. (IF=15.4)

10.Zhao H#, Wang X#, Yi P, Si Y, Tan P, He J, Yu S, Ren Y, Ma Y, Zhang J, Wang D*, Wang F*, Yu J*. KSRP specifies monocytic and granulocytic differentiation through regulating miR-129 biogenesis and RUNX1 expression. Nat Commun. 2017, 8(1): 1428-1428. (IF=12.4)