劉曉輝,研究員,博士生導(dǎo)師。獲得國(guó)家級(jí)優(yōu)秀青年人才項(xiàng)目資助。       院校引進(jìn)人才,2023年加入院校,曾在美國(guó)斯克里普斯研究所、哈佛醫(yī)學(xué)院進(jìn)行博士后研究工作。
劉曉輝
中國(guó)醫(yī)學(xué)科學(xué)院藥物研究所
助理教授
2023-07-01
藥學(xué)
藥物化學(xué)
xiaohuiliu@imm.ac.cn
劉曉輝,研究員,博士生導(dǎo)師。獲得國(guó)家級(jí)優(yōu)秀青年人才項(xiàng)目資助。       院校引進(jìn)人才,2023年加入院校,曾在美國(guó)斯克里普斯研究所、哈佛醫(yī)學(xué)院進(jìn)行博士后研究工作。
長(zhǎng)期從事靶向RNA的小分子藥物開發(fā),以第一作者或共同第一作者在Nature,J. Am. Chem. Soc.,Angew. Chem. Int. Ed.,Cell Chem. Biol.等期刊發(fā)表論文多篇;獲得授權(quán)發(fā)明專利1項(xiàng)。主持國(guó)家自然科學(xué)基金面上項(xiàng)目、京津冀基礎(chǔ)研究合作專項(xiàng)等多項(xiàng)科技項(xiàng)目。任期刊Pharmaceutical Science Advances青年編委。
1. Ting Dong#*, Fabao Zhao#, Mengmeng Wang#, Kaige Lyu#, Jiayu Zhu, Wenru Zhang, Wenzhe Li, Yixuan An, Na Liu, Akhand Pratap Singh, Yue Yang, Dongwei Kang*, Xiaohui Liu*. G3BP1/2 -targeting PROTAC disrupts stress granules dependent ATF4 migracytosis as cancer therapy, J. Am. Chem. Soc. 2025, 147(1), 446-461 2. Yuquan Tong#, Yeongju Lee#, Xiaohui Liu#, Jessica L. Childs-Disney#, Blessy M. Suresh, Raphael I. Benhamou, Chunying Yang, Weimin Li, Matthew G. Costales, Hafeez S. Haniff, Sonja Sievers, Daniel Abegg, Tristan Wegner, Tiffany O. Paulisch, Elizabeth Lekah, Maison Grefe, Gogce Crynen, Montina Van Meter, Tenghui Wang, Quentin M. R. Gibaut, John L. Cleveland, Alexander Adibekian, Frank Glorius*, Herbert Waldmann*, Matthew D. Disney*. Nature, 2023, 618:169–179. (F1000) 3. Hafeez S. Haniff#, Xiaohui Liu#, Yuquan Tong, Samantha M. Meyer, Laurent Knerr, Malin Lemurell, Daniel Abegg, Haruo Aikawa, Alexander Adibekian, Matthew D. Disney*. A structure-specific small molecule inhibits a miRNA-200 family member precursor and reverses a type 2 diabetes phenotype. Cell Chem. Biol. 2022, 29(2):300-311.e10. 4. Peiyuan Zhang#, Xiaohui Liu#, Daniel Abegg, Toru Tanaka, Yuquan Tong, Raphael I. Benhamou, Jared Baisden, Gogce Crynen, Samantha M. Meyer, Michael D. Cameron, Arnab K. Chatterjee, Alexander Adibekian, Jessica L. Childs-Disney, Matthew D. Disney*. Reprogramming of protein-targeted small molecule medicines to RNA via ribonuclease targeting chimeras. J. Am. Chem. Soc. 2021, 143(33):13044-13055. (F1000) 5. Xiaohui Liu#, Hafeez S#. Haniff, Jessica L. Childs-Disney, Anton Shuster, Haruo Aikawa, Alexander Adibekian, Matthew D. Disney*, Targeted Degradation of the Oncogenic MicroRNA 17-92 Cluster by Structure-Targeting Ligands. J. Am. Chem. Soc. 2020, 142(15):6970-6982.午夜92福利1000,午夜92福利1000,久久国产亚洲高清观看5388,美女不拍网站免费观看,欧美***天天久久综合精品,中文字幕日韩系列中文字幕,综合久久国产九一剧情麻豆,丰满人妻在线免费视频,奶子大逼又嫩操起来真爽