王朝輝，研究員，博士生導(dǎo)師。2006年畢業(yè)于鄭州大學(xué)，獲得藥物制劑學(xué)士學(xué)位。2009年畢業(yè)于沈陽(yáng)藥科大學(xué)，獲得藥劑學(xué)碩士學(xué)位。2012年畢業(yè)于北京大學(xué)，獲得藥劑學(xué)博士學(xué)位。獲得國(guó)家級(jí)優(yōu)秀青年人才項(xiàng)目資助，以及遼寧省自然科學(xué)獎(jiǎng)?wù)撐念愐坏泉?jiǎng)等榮譽(yù)。
     院校引進(jìn)人才，2020年加入院校，曾在美國(guó)普渡大學(xué)、德克薩斯大學(xué)西南醫(yī)學(xué)中心從事科學(xué)研究工作。

長(zhǎng)期從事智能藥物遞送系統(tǒng)及其在腫瘤免疫治療中的應(yīng)用研究。立足于實(shí)體瘤療效不佳的難題，系統(tǒng)性探索了遞送載體的理性設(shè)計(jì)，提出和發(fā)展了不同作用機(jī)制協(xié)同增效的抗腫瘤免疫治療策略。迄今發(fā)表學(xué)術(shù)論文40余篇，包括以第一和通訊作者在Nature Nanotechnology、Advanced Materals、Angewandte Chemie International Edition、Nano Letters、ACS Nano等期刊發(fā)表論文多篇，承擔(dān)多項(xiàng)國(guó)家和省部級(jí)科研項(xiàng)目，參與英文專著及十四五規(guī)劃教材各1章節(jié)，授權(quán)美國(guó)及澳大利亞專利各1項(xiàng)，研究成果技術(shù)轉(zhuǎn)移2項(xiàng)。

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1. Zhou M#, Liang S#, Wang J#, Hai L#, Peng Y, Xiong Q, Liu D, Ma K, Yun K, Wang Z*. A Rationally Designed Cyclic Dinucleotide Amplifier Potentiating STING Activation for Cancer Immunotherapy. Advanced Functional Materials 2025, 35(24): 2414918. (IF=18.5)

2. Liang S#, Ma H#, Liu Y, Hai L, Tian Y, Sun Y, Wang Z*. Nano-immunomodulator amplifies STING activation in tumor-associated macrophages for cancer immunotherapy. Journal of Controlled Release 2025, 383: 113846. (IF=11.5)

3. Liu D#, Liang S, Ma K, Meng Q, Li X, Wei J, Zhou M, Yun K, Pan Y, Rao L*, Chen X*, Wang Z*. Tumor Microenvironment-Responsive Nanoparticles Amplifying STING Signaling Pathway for Cancer Immunotherapy. Advanced Materials 2024, 36(5): e2304845. (IF=27.4)

4. Peng Y#, Liang S, Liu D, Ma K, Yun K, Zhou M, Hai L, Xu M, Chen Y, Wang Z*. Multi‐Metallic Nanosheets Reshaping Immunosuppressive Tumor Microenvironment through Augmenting cGAS‐STING Innate Activation and Adaptive Immune Responses for Cancer Immunotherapy. Advanced Science 2024, 11(38): 2403347. (IF=15.1)

5. Liang S#, Ma M#, Li X#, Yun K, Meng Q, Ma K, Liu D, Yue L, Rao L*, Chen X*, Wang Z*. A Guanidinobenzol-Rich Polymer Overcoming Cascade Delivery Barriers for CRISPR-Cas9 Genome Editing. Nano Letters 2024, 24(23): 6872-6880. (IF=10.8，封面)

6. Pan Y#, Liu L, Zhang J, Liang S, Parshad B, Lai J, Ma L*, Wang Z*, Rao L*. Genetically Engineered Nanomodulators Elicit Potent Immunity against Cancer Stem Cells by Checkpoint Blockade and Hypoxia Relief. Bioactive Materials 2024, 38: 31-44. (IF=18.9)

7. D Liu#, S Liang#, K Ma, K Yun, M Zhou, J Yao, L Hai, Y Peng, Z Wang*. A bi-adjuvant nanovaccine amplifying STING activation for cancer immunotherapy. Nano Today 2024, 57: 102372. (IF=13.1)

8. Liang S#, Yao J, Liu D, Rao L^*, Chen X^*, Wang Z^*. Harnessing Nanomaterials for Cancer Sonodynamic Immunotherapy. Advanced Materials 2023, 35(33): e2211130. (IF=27.4)

9. Luo M^#, Wang H^#, Wang Z^#, Cai H, Lu Z, Li Y, Du M, Huang G, Wang C, Chen X, Porembka M, Lea J, Frankel A, Fu Y, Chen Z*, Gao J*. A STING-activating nanovaccine for cancer immunotherapy. Nature Nanotechnology 2017, 12: 648-654. (IF=39.2，ESI高被引)

10. Wang Z#, Luo M#, Mao C, Wei Q, Zhao T, Li Y, Huang G, Gao J*. A redox-activatable fluorescent sensor for the high-throughput quantification of cytosolic delivery of macromolecules. Angewandte Chemie International Edition 2017, 129: 1339-1343. (IF=16.9)