汪一波，1980年生，籍貫安徽，遺傳學(xué)生物學(xué)家，阜外醫(yī)院研究員，博士生導(dǎo)師。1997年考入浙江大學(xué)生物技術(shù)專(zhuān)業(yè)，2001年獲得學(xué)士學(xué)位。2001年在中國(guó)協(xié)和醫(yī)科大學(xué)遺傳學(xué)專(zhuān)業(yè)攻讀直博學(xué)位，從事心血管病易感基因的變異研究。2008年進(jìn)入哈佛大學(xué)醫(yī)學(xué)院進(jìn)行博士后研究工作，主要研究疾病中翻譯起始機(jī)制干預(yù)。2006年升為助理研究員。2010年為副研究員。2014年為研究員。

研究方向：心血管病遺傳學(xué) 以心臟血管疾病人群或患者為研究對(duì)象，包括動(dòng)脈硬化、血管畸形、主動(dòng)脈夾層、心肌病、高血壓等，尋找可能參與的胚系和體細(xì)胞基因突變、CNV、融合基因等。對(duì)相關(guān)基因的功能或基因突變的功能進(jìn)行研究，體外和動(dòng)物水平闡明參與疾病發(fā)生發(fā)展的機(jī)制。對(duì)潛在的靶點(diǎn)進(jìn)行臨床轉(zhuǎn)化，找到合適的靶向治療方案。

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1. Bing Cui#, Xiao Xiao#, Jin’e Wang, Hongrui Wang, Cunjin Wu, Yupeng Yan, Jun Zheng, JingJun Wang, Yuru Zong, Yu Zhang, Rutai Hui, A. Martin Gerdes, Yibo Wang*. Low THRB (thyroid hormone receptor beta) Promoter Methylation Levels in Peripheral Blood Leukocytes Induced By Systematic Inflammation Are Involved in Low Thyroid Hormone Function in Metabolic Syndrome. Hypertension. 2021;78:1005–1015. (IF=10.19)

2. Yupeng Yan#, Jin'e Wang, Liang Yu, Bing Cui, Hongrui Wang, Xiao Xiao, Yu Zhang, Jun Zheng, Jingjun Wang, Rutai Hui, Yibo Wang*. ANKRD36 Is Involved in Hypertension by Altering Expression of ENaC Genes. Circulation Research. 2021;129:1067–1081.(IF=23.213)

3. Tao Hong #, Xiao Xiao #, Jian Ren#, Bing Cui, Yuru Zong, Jian Zou, Zqi Kou, Nan Jiang, Guolu Meng, Gao Zeng, Yongzhi Shan, Hao Wu , Zan Chen, Jiantao Liang, Xinru Xiao, Jie Tang, Yukui Wei, Ming Ye, Liyong Sun, Guilin Li, Peng Hu, Rutai Hui, Hongqi Zhang, Yibo Wang*. Somatic MAP3K3 and PIK3CA mutations in sporadic cerebral and spinal cord cavernous malformations. Brain. 2021: 144; 2648–2658. (IF= 15.255)

4. Tao Hong#, Yupeng Yan#, Jingwei Li, Ivan Radovanovic, Xiangyuan Ma, Yang W. Shao, Jiaxing Yu, Yongjie Ma, Peng Zhang, Feng Ling, Shuchen Huang, Hongqi Zhang and Yibo Wang*. High prevalence of KRAS/BRAF somatic mutations in brain and spinal cord arteriovenous malformations. Brain. 2019;142(1):23-34.(IF= 13.501,C=100)

5. Mingli He#, Jin’e Wang#*, Na Liu, Xiao Xiao, Shan Geng, Pin Meng, Niu Ji, Yong’an Sun, Bingchao Xu, Yingda Xu, Xinyu Zhou, Guanghui Zhang, Xiaobing He, Zenglin Cai, Zaipo Li, Bei Wang, Bei Xu, Rutai Hui, Yibo Wang*. Effects of Blood Pressure in the Early Phase of Ischemic Stroke and Stroke Subtype on Poststroke Cognitive Impairment. Stroke. 2018;49(7):1610-1617. (IF=6.239)

6. Mingli He#, Jin'e Wang#, Ling Gong, Qing Dong, Niu Ji, Houxun Xing, Yuan Zhou, Sizhou Qin,Huizheng Wang, Huamin Zhang, Rutai Hui* and Yibo Wang*. Community-based stroke system of care for Chinese rural areas. Stroke. 2014;45:2385-2390. (IF=5.968)

7. Yibo Wang#*, Jing Xu#, Jinxing Chen, Xiaohan Fan, Yu Zhang, Weifeng Yu, Jibin Liu, Rutai Hui*. Promoter variants of VTN are associated with vascular disease. International Journal of Cardiology. 2013;168 (1): 163–168. (IF=6.463)

8. Yibo Wang#*, Bin Lv#, Jinxing Chen, Yu Zhang, Fang Luo, Na Lu, Kai Sun, Zhihui Hou, Huili Cao, Irfan Zeb, Matthew Budoff and Rutai Hui*. Intramural coronary arterial course is associated with coronary arterial stenosis and prognosis of major cardiac events. Arterioscler Thromb Vasc Biol. 2013;33:439-444. (IF=6.640)

9. Yibo Wang#, Yi Zheng#, Weili Zhang, Hui Yu, Kejia Lou,Yu Zhang,Qin Qin, Bingrang Zhao, Ying Yang, Rutai Hui*.Polymorphisms of kdr gene are associated with coronary heart disease.Journal of the American College of Cardiology. Journal of the American College of Cardiology. 2007;50(8):760-767. (IF=10.345,C=100)

10. Yibo Wang#, Weili Zhang, Yuhui Zhang, Yuejin Yang, Lizhong Sun, Shengshou Hu, Jilin Chen, Channa Zhang, Yi Zheng, Yisong Zhen, Kai Sun, Chunyan Fu, Tao Yang, Jianwei Wang, Jing Sun, Haiying Wu, Wayne C. Glasgow and Rutai Hui*. VKORC1 haplotypes are associated with arterial vascular diseases. Circulation. 2006;113(12):1615-1621. (IF=11.786,C=100)